Tex101 is essential for male fertility by affecting sperm migration into the oviduct in mice
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منابع مشابه
Tex101 is essential for male fertility by affecting sperm migration into the oviduct in mice.
Dear Editor, Sperm transport in the female genital tract is physiologically important for mammalian fertilization. The female reproductive system contains multiple natural selective barriers, such as successful uterotubal junction (UTJ) migration and zona pellucida (ZP) binding, to ensure sperm with normal motility and morphology to transmit into oviduct for fertilization (Yanagimachi, 1994; Ik...
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TEX101, a germ cell-specific glycosyl-phosphatidylinositol (GPI)-anchored glycoprotein, is associated with Ly6k during spermatogenesis in testis. Although both Tex101(-/-) and Ly6k(-/-) mice can produce morphologically intact spermatozoa, both knockout mice show an infertile phenotype due to a disorder of spermatozoa to migrate into the oviduct. Since Ly6k specifically interacts with TEX101, co...
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ژورنال
عنوان ژورنال: Journal of Molecular Cell Biology
سال: 2013
ISSN: 1759-4685,1674-2788
DOI: 10.1093/jmcb/mjt031